Transcranial random noise stimulation (tRNS) improves hot and cold executive functions in children with attention deficit-hyperactivity disorder (ADHD).

Children with attention deficit-hyperactivity disorder (ADHD) have impaired hot and cold executive functions, which is thought to be related to impaired ventromedial and dorsolateral prefrontal cortex (vmPFC and dlPFC) functions. The present study aimed to assess the impact concurrent stimulation of dlPFC and vmPFC through transcranial random noise stimulation (tRNS), a non-invasive brain stimulation tool which enhances cortical excitability via application of alternating sinusoidal currents with random frequencies and amplitudes over the respective target regions on hot and cold executive functions. Eighteen children with ADHD received real and sham tRNS over the left dlPFC and the right vmPFC in two sessions with one week interval. The participants performed Circle Tracing, Go/No-Go, Wisconsin Card Sorting, and Balloon Analogue Risk Tasks during stimulation in each session. The results showed improved ongoing inhibition, prepotent inhibition, working memory, and decision making, but not set-shifting performance, during real, as compared to sham stimulation. This indicates that simultaneous stimulation of the dlPFC and the vmPFC improves hot and cold executive functions in children with ADHD.

The role of prefrontal cortex and temporoparietal junction in interpersonal comfort and emotional approach.

Our perception of physical distance to individuals and stimuli is influenced by our mental distance and relatedness. The present study aimed to investigate the role of the dorsolateral prefrontal cortex (dlPFC), ventromedial prefrontal cortex (vmPFC), and right temporoparietal junction (rTPJ) in interpersonal comfortable distance and approach behaviors towards emotional stimuli. Twenty healthy volunteers received brain stimulation in four separate sessions with a one-week interval, including anodal left dlPFC, anodal right vmPFC, anodal rTPJ, and sham condition, with an extracranial return electrode. Our results revealed an increase in interpersonal distance during anodal rTPJ stimulation and a decrease in distance to positive pictures during anodal vmPFC stimulation. These findings suggest that the rTPJ plays a role in the perceptual component of self-other distancing, while the vmPFC is involved in approaching positive emotions.

Cognitive training for modifying interpretation and attention bias in depression: Relevance to mood improvement and implications for cognitive intervention in depression.

Depressed individuals interpret ambiguous information more negatively and this has been suggested a central component in cognitive models of depression. In this study we investigated the effectiveness of the interpretation modification training on modifying interpretation bias in depression and its association with symptoms reduction. In a double-blind, randomized controlled design, twenty-two depressed individuals (mean age = 19.86, SD = 1.16) were randomly assigned to the experimental and control groups. They completed 10 sessions of cognitive training with the Ambiguous Hallmark Program (AHP) over 5 weeks. Participants' interpretation bias and their depressive scores were assessed and compared before and after the intervention. Results showed that the AHP significantly decreased negative interpretation in the experimental group. Additionally, a significant decrease in the depressive scores was also observed in the intervention group compared to the control group. We also observed the transfer of learning from the AHP training to another interpretation bias task. The AHP can significantly modify negative interpretations and symptoms in depression providing preliminary supporting evidence for its clinical application especially in mild-to-moderate depression. Improved cognitive control over emotional information and unbiased attention to them could explain effects of the Interpretation modification paradigm. Further studies need to examine the efficacy of the AHP as a potential cognitive intervention in depression.

Effect of exercise augmentation of cognitive behavioural therapy for the treatment of suicidal ideation and depression.

BACKGROUND: Suicidal ideation and depression are prevalent and costly conditions that reduce quality of life. This study was designed to determine the efficacy of exercise as an adjunct to cognitive behavioural therapy (CBT) for suicidal ideation and depression among depressed individuals. METHODS: In a randomized clinical trial, 54 mildly to moderately depressed patients (54% female, mean age=48.25) were assigned to a combined CBT and exercise group or to a CBT only group. Both groups received one weekly session of therapy for 12 weeks, while the combined group also completed exercise three times weekly over the same period. Self-reported suicidal ideation, depression, and activities of daily living were measured at the beginning and the end of treatment. RESULTS: Multilevel modelling revealed greater improvements in suicidal ideation, depression, and activities of daily living in the combined CBT and exercise group, compared to the CBT only group. LIMITATIONS: No follow-up data were collected, so the long-term effects (i.e., maintenance of gains) is unclear. CONCLUSIONS: The findings revealed that exercise adjunct to CBT effectively decreases both depressive symptoms and suicidal ideation in mildly to moderately depressed individuals.

Spiritual Care Training for Mothers of Children with Cancer: Effects on Quality of Care and Mental Health of Caregivers.

BACKGROUND: The purpose of this study was to explore the effectiveness of a spiritual care training package in maternal caregivers of children with cancer. MATERIALS AND METHODS: This study was a quasi-experimental study with pretest and posttest design consisting of a sample of 42 mothers of children diagnosed as having cancer. Participants were randomly assigned to either an experimental or a control group. The training package consisted of seven group training sessions offered in a children's hospital in Tehran. All mothers completed the Spirituality and Spiritual Care Rating Scale (SSCRS) and the Depression, Anxiety and Stress Scale (DASS-21) at pre and post test and after a three month follow up. RESULTS: There was significant difference between anxiety and spiritual, religious, Personalized care and total scores spiritual care between the intervention and control groups at follow-up (P<0.001).There was no statistically significant difference in stress and depression scores between the intervention and the control groups at follow-up. CONCLUSIONS: Findings show that spiritual care training program promotes spirituality, personalized care, religiosity and spiritual care as well as decreasing anxiety in mothers of children with cancer and decreases anxiety. It may be concluded that spiritual care training could be used effectively in reducing distressful spiritual challenges in mothers of children with cancer.

Effects of Chronic Illness on the Quality of Life in Psychiatric out patients of the Iraq - Iran War.

OBJECTIVE: Quality of life measures can provide an important source of medical information for promoting the health status of chronically ill patients. The purpose of the present study was to evaluate health related quality of life in psychiatric veterans of the Iraq- Iran war of the 1980s. METHODS: They were out patients diagnosed with various psychiatric symptoms. The present study used a cross sectional design, in which 971 psychiatric veterans were selected by Systematic-randomized sampling and evaluated using the SF36 questionnaire. RESULTS: Findings revealed that veterans who suffered from one or more chronic conditions/illnesses reported significantly more bodily pain and significantly less vitality, mental and general health compared to those veterans without chronic conditions. Moreover, specific aspects of poor quality of life were more salient in specific chronic conditions/illnesses than others. CONCLUSION: Based on these findings, chronic conditions, especially respiratory problems, can have a detrimental effect on the quality of life in psychiatric war veterans.

Forgiveness in relation to attachment style and consanguine marriage in Iranian married individuals.

The aim of this study was to compare forgiveness in secure and insecure Iranian married couples. Whether marriage had occurred within the family (consanguine) or not (non-consanguine) was also considered. 400 married participants completed the Family Forgiveness Scale and the Adult Attachment Questionnaire. Analysis of reported forgiveness within the marital family showed that, although there was no significant difference between secure and insecure participants in overall forgiveness, secure participants rated "reparation" and "resolution" higher, whereas insecure participants rated "realization" and "recognition" higher. Comparing the experience of forgiveness in the family of origin, securely attached couples not only reported significantly more overall forgiveness but reported more "realization" and "resolution" while forgiving. Some interesting sex differences were also found, as individuals in consanguine vs non-consanguine couples differed in mean "recognition" in the forgiveness process.

Comparing the effectiveness of Cognitive Behavioral Therapy and Stages of Change Model on Improving Abstinence Self-Efficacy in Iranian Substance Dependent Adolescents.

OBJECTIVE: The present study was conducted to compare the effectiveness of two therapeutic approaches, namely, Cognitive Behavioral Therapy (CBT) and Stages of Change Model (SOC) on improving abstinence self-efficacy in adolescent addicts. METHODS: Forty five self-referred adolescent addicts were randomly selected to take part in this study. Initial assessment was made using the following questionnaires: The University of Rhodes Island Change Assessment (URICA), General Self-Efficacy Questionnaire (GSE), and Adolescent Self-Efficacy Scale (ASES). Subjects were placed in two experimental (CBT, SOC) groups and one control group (three groups in all). The two experimental groups received twice a week interventions for 12 weeks and then were post tested and once again reassessed in a two-month follow up. RESULTS: RESULTS clearly highlighted the effectiveness of the two models of intervention on general and special self-efficacy. The effectiveness of SOC proved greater than CBT on general self-efficacy in both posttest as well as the two-month follow up. Whereas CBT was more effective than SOC on special self-efficacy in posttest, SOC was more effective than CBT on dimensions of special self-efficacy in the follow up assessment. CONCLUSIONS: Both CBT and SOC improve general and situational self-efficacy. Hence SOC may have more permanent and long lasting effect on self-efficacy than CBT.

What is the relationship between alexithymia and ego defense styles? A correlational study with Iranian students.

The relationship between alexithymia and ego defense styles was investigated in a sample of Iranian students. The association between the components of alexithymia including difficulty in identifying and describing feelings and externally oriented thinking with ego defense styles including mature, neurotic, and immature defense styles was investigated in two hundred and eighty six students in the University of Tehran. All participants were asked to complete the Farsi version of the Toronto Alexithymia Scale (FTAS-20) and Defense Styles Questionnaire (DSQ). Results showed that there was a significant negative correlation between alexithymia and mature defense style as well as a significant positive association with neurotic and immature defense styles. It is concluded that alexithymia is associated with ego defense mechanisms. Results are discussed in terms of the implications of the present results in terms of designing possible modification and intervention programmes as well as answering important theoretical questions.

Perfectionism, anger, and anger rumination.

Anger and anger rumination are considered to be detrimental to both physical and psychological well being. Furthermore, perfectionism, as a personality construct, seems to be related to various types of maladjustment. Whereas perfectionism has been characterized as being positive when an individual derives pleasure from striving for excellence yet recognizes and accepts individual limitations, it is deemed negative when the individual has unrealistic expectations and is never satisfied with his or her performance. The present study examined whether positive and negative perfectionism was associated with anger and anger rumination. The Farsi version of the Positive and Negative Perfectionism Scale and the Farsi version of the Anger Rumination Scale, as well as Spielberger's State-Trait Anger Scale were completed by 384 Iranian students. Results showed that anger and anger rumination were, as expected, associated negatively with positive perfectionism and associated positively with negative perfectionism. Positive perfectionism enables individuals to strive for success in a flexible manner and, thus, to experience satisfaction and pleasure rather than dissatisfaction, frustration, and anger. Conversely, negative perfectionism makes individuals vulnerable to emotional distress such as predisposition to experience anger and anger rumination through setting high standards for performance, overgeneralization of perceived failures, negative self-evaluation, self-blame, and measuring self-worth in terms of unachievable goals of accomplishment and productivity. Hence, perfectionism may be regarded as having both adaptive and maladaptive aspects with regard to health.